Course Syllabus

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 Approfondire la conoscenza sulla fisiologia del sonno e sui suoi disturbi soprattutto per quello che riguarda le ripercussioni cardiovascolari e sistemiche.

La medicina del Sonno è una disciplina, relativamente recente ma introdotta in tutta Europa nel percorso formativo del personale sanitario.

La conoscenza della fisiologia del sonno e dei principali disturbi sonno-correlati forniscono allo studente in formazione importanti strumenti diagnostici-terapeutici con ripercussioni potenziali sullo stato di salute generale dei pazienti. Il problema più frequente durante il sonno, oltre l'insonnia, è certamente il Sindrome delle Apnee Ostruttive nel Sonno (sindrome da apnea ostruttiva del sonno), che comprende un ampio spettro di condizioni cliniche alla base delle quali è una stenosi più o meno marcata delle vie aeree superiori durante il sonno particolarmente frequenti in pazienti obesi e soprappeso. L'OSAS è una patologia con frequenza crescente: circa due milioni di persone in Italia sono affetti da questa malattia ed è una patologia di guida. Inoltre sempre maggiori evidenze supportano lo stretto legame tra i disturbi del sonno, in particolare i disturbi del sonno e le patologie cerebro e cardiovascolari. Da qui l'importanza di una maggiore consapevolezza del problema da parte di medici, studenti e personale infermieristico.

Iscrizione al quinto anno e successivi dei Corsi di Laurea in Medicina e Chirurgia.

Il corso si basa su:

 - Lezioni teoriche sia mediante video sia mediante proiezione power point, tenute dal titolare e da neurologi specializzati nello studio del sonno.

- Dimostrazione delle metodiche per la registrazione del sonno e dei parametri cardiovascolari nelle 24 ore e per lo studio della regolazione nervosa autonoma del circolo.

1: Lombardi C, Tobaldini E, Montano N, Losurdo A, Parati G. Obstructive Sleep

Apnea Syndrome (OSAS) and Cardiovascular System. Med Lav. 2017 Aug

28;108(4):276-282. doi: 10.23749/mdl.v108i4.6427. PubMed PMID: 28853425.

 

 

2: Parati G, Lombardi C, Castagna F, Mattaliano P, Filardi PP, Agostoni P;

Italian Society of Cardiology (SIC) Working Group on Heart Failure members. Heart

failure and sleep disorders. Nat Rev Cardiol. 2016 Jul;13(7):389-403. doi:

10.1038/nrcardio.2016.71. Epub 2016 May 12. Review. PubMed PMID: 27173772.

 

 

3: Parati G, Ochoa JE, Lombardi C, Bilo G. Blood pressure variability:

assessment, predictive value, and potential as a therapeutic target. Curr

Hypertens Rep. 2015 Apr;17(4):537. doi: 10.1007/s11906-015-0537-1. Review. PubMed

PMID: 25790801.

 

 

4: Parati G, Ochoa JE, Bilo G, Mattaliano P, Salvi P, Kario K, Lombardi C.

Obstructive sleep apnea syndrome as a cause of resistant hypertension. Hypertens

Res. 2014 Jul;37(7):601-13. doi: 10.1038/hr.2014.80. Epub 2014 May 8. Review.

PubMed PMID: 24804613.

 

 

5: Parati G, Ochoa JE, Lombardi C, Bilo G. Assessment and management of

blood-pressure variability. Nat Rev Cardiol. 2013 Mar;10(3):143-55. doi:

10.1038/nrcardio.2013.1. Epub 2013 Feb 12. Review. Erratum in: Nat Rev Cardiol.

2014 Jun;11(6):314. PubMed PMID: 23399972.

 

 

6: Parati G, Lombardi C, Hedner J, Bonsignore MR, Grote L, Tkacova R, Lévy P,

Riha R, Bassetti C, Narkiewicz K, Mancia G, McNicholas WT; EU COST Action B26

members. Recommendations for the management of patients with obstructive sleep

apnoea and hypertension. Eur Respir J. 2013 Mar;41(3):523-38. doi:

10.1183/09031936.00226711. Epub 2013 Feb 8. PubMed PMID: 23397300.

 

 

7: Parati G, Lombardi C, Hedner J, Bonsignore MR, Grote L, Tkacova R, Levy P,

Riha R, Bassetti C, Narkiewicz K, Mancia G, McNicholas WT; European Respiratory

Society; EU COST ACTION B26 members. Position paper on the management of patients

with obstructive sleep apnea and hypertension: joint recommendations by the

European Society of Hypertension, by the European Respiratory Society and by the

members of European COST (COoperation in Scientific and Technological research)

ACTION B26 on obstructive sleep apnea. J Hypertens. 2012 Apr;30(4):633-46. doi:

10.1097/HJH.0b013e328350e53b. PubMed PMID: 22406463.

 

 

8: Parati G, Lombardi C, Narkiewicz K. Sleep apnea: epidemiology,

pathophysiology, and relation to cardiovascular risk. Am J Physiol Regul Integr

Comp Physiol. 2007 Oct;293(4):R1671-83. Epub 2007 Jul 25. Review. PubMed PMID: 17652356.

Verifica interattiva a fine corso


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Increase the knowledge about sleep physiology and influence of sleep on cardiovascular systems, both in physiological and pathological conditions.

Sleep Medicine is a relatively recent discipline that has been introduced throughout Europe in the training of health workers. The knowledge of sleep physiology and of the main sleep disorders provides the student important  diagnostic-therapeutic tools with potential effects on the general health status of the patients. The most prevalent sleep disorder , besides insomnia, is certainly the Obstructive Sleep Apnea Syndrome (obstructive sleep apnea syndrome), which includes a wide spectrum of clinical conditions that are related to upper airway narrowing during sleep, particularly in obese and overweight patients. OSAS is a pathology with increasing frequency: about two million people in Italy are affected by this disease. Excessive daytime sleepiness is often referred by OSAS patients, with reduced performance at work and driving. Furthermore, increasing evidence supports the close link between sleep disorders, in particular sleep related breathing disorders to the cerebral and cardiovascular diseases. High prevalence and important complications related to OSAS stimulate a growing awareness by clinicians and students and nursing staff

Medical students at 5rd year


Teaching methodology:

- Theoretical lessons (slides, power point presentations by teachers with Sleep disorders expertise )

- Theoretical and practical training in the use of dynamic monitors for sleep and cardiovascular parameters


1: Lombardi C, Tobaldini E, Montano N, Losurdo A, Parati G. Obstructive Sleep

Apnea Syndrome (OSAS) and Cardiovascular System. Med Lav. 2017 Aug

28;108(4):276-282. doi: 10.23749/mdl.v108i4.6427. PubMed PMID: 28853425.

 

 

2: Parati G, Lombardi C, Castagna F, Mattaliano P, Filardi PP, Agostoni P;

Italian Society of Cardiology (SIC) Working Group on Heart Failure members. Heart

failure and sleep disorders. Nat Rev Cardiol. 2016 Jul;13(7):389-403. doi:

10.1038/nrcardio.2016.71. Epub 2016 May 12. Review. PubMed PMID: 27173772.

 

 

3: Parati G, Ochoa JE, Lombardi C, Bilo G. Blood pressure variability:

assessment, predictive value, and potential as a therapeutic target. Curr

Hypertens Rep. 2015 Apr;17(4):537. doi: 10.1007/s11906-015-0537-1. Review. PubMed

PMID: 25790801.

 

 

4: Parati G, Ochoa JE, Bilo G, Mattaliano P, Salvi P, Kario K, Lombardi C.

Obstructive sleep apnea syndrome as a cause of resistant hypertension. Hypertens

Res. 2014 Jul;37(7):601-13. doi: 10.1038/hr.2014.80. Epub 2014 May 8. Review.

PubMed PMID: 24804613.

 

 

5: Parati G, Ochoa JE, Lombardi C, Bilo G. Assessment and management of

blood-pressure variability. Nat Rev Cardiol. 2013 Mar;10(3):143-55. doi:

10.1038/nrcardio.2013.1. Epub 2013 Feb 12. Review. Erratum in: Nat Rev Cardiol.

2014 Jun;11(6):314. PubMed PMID: 23399972.

 

 

6: Parati G, Lombardi C, Hedner J, Bonsignore MR, Grote L, Tkacova R, Lévy P,

Riha R, Bassetti C, Narkiewicz K, Mancia G, McNicholas WT; EU COST Action B26

members. Recommendations for the management of patients with obstructive sleep

apnoea and hypertension. Eur Respir J. 2013 Mar;41(3):523-38. doi:

10.1183/09031936.00226711. Epub 2013 Feb 8. PubMed PMID: 23397300.

 

 

7: Parati G, Lombardi C, Hedner J, Bonsignore MR, Grote L, Tkacova R, Levy P,

Riha R, Bassetti C, Narkiewicz K, Mancia G, McNicholas WT; European Respiratory

Society; EU COST ACTION B26 members. Position paper on the management of patients

with obstructive sleep apnea and hypertension: joint recommendations by the

European Society of Hypertension, by the European Respiratory Society and by the

members of European COST (COoperation in Scientific and Technological research)

ACTION B26 on obstructive sleep apnea. J Hypertens. 2012 Apr;30(4):633-46. doi:

10.1097/HJH.0b013e328350e53b. PubMed PMID: 22406463.

 

 

8: Parati G, Lombardi C, Narkiewicz K. Sleep apnea: epidemiology,

pathophysiology, and relation to cardiovascular risk. Am J Physiol Regul Integr

Comp Physiol. 2007 Oct;293(4):R1671-83. Epub 2007 Jul 25. Review. PubMed PMID: 17652356.

Interactive verification at the course conclusion.

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Key information

Field of research
NN
ECTS
2
Term
Annual
Activity type
Elective
Course Length (Hours)
14
Degree Course Type
6-year single cycle Master Degree

Staff

    Teacher

  • CL
    Carolina Lombardi

Students' opinion

View previous A.Y. opinion

Enrolment methods

Manual enrolments