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Percorso della pagina
  1. Medicine and Surgery
  2. Single Cycle Master Degree (6 years)
  3. Medicine and Surgery [H4104D - H4102D]
  4. Courses
  5. A.A. 2019-2020
  6. 1st year
  1. Histology
  2. Summary
Unità didattica Course full name
Histology
Course ID number
1920-1-H4102D007-H4102D021M
Course summary SYLLABUS

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Back to Fundamentals of Human Morphology

Course Syllabus

  • Italiano ‎(it)‎
  • English ‎(en)‎
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Obiettivi

Gli studenti saranno in grado di descrivere la struttura e l’ultrastruttura delle cellule eucariote, la funzione e la morfologia di ciascun organello; di descrivere la struttura e le caratteristiche morfo-funzionali dei tessuti umani (epiteliale, connettivo, muscolare e nervoso) e di descrivere i principali eventi della gametogenesi e delle prime fasi di embriogenesi.

Contenuti sintetici

Vedere “Fundamentals of Human Morphology”

Programma esteso

- Istologia e i suoi metodi di studio.

- Citologia: proprietà generali delle cellule eucariote.

- Membrana plasmatica: struttura, composizione molecolare, funzioni.

- Connessioni cellulari: tight junctions, gap junctions, desmosomi.

- Citosol: composizione molecolare e funzioni

- Organelli citoplasmatici: mitocondri, ribosomi, reticolo endoplasmatico (rugoso e liscio), complesso di Golgi, lisosomi, perossisomi.

- Citoscheletro: microtubuli, filamenti di actina e filamenti intermedi

- Trafficking, sorting e secrezione di proteine.

- Nucleo e nucleolo

- Morte cellulare: apoptosi e necrosi.

 

Tessuti:

- Tessuto epiteliale: epiteli di rivestimento e epiteli ghiandolari. Microvilli, ciglia, flagello, stereociglia. Membrana basale. 

- Tessuto connettivo: cellule, sostanza fondamentale, fibre. Tipi di tessuti connettivi: lasso, irregolare denso, regolare denso, elastico.

- Tessuto adiposo: tessuto adiposo uniloculare e multiloculare.

- Cartilagine: ialina, elastica e fibrocartilaginea.

- Osso: cellule ossee, matrice ossea. Tipi di osso: tessuto osseo primario e secondario; osso compatto e spugnoso.

Istogenesi: ossificazione intramembranosa e endocondrale. Rimodellamento e riparazione.

- Tessuto muscolare: muscolo liscio, scheletrico e cardiaco, Contrazione. Rigenerazione.

- Tessuto nervoso: neuroni e cellule gliali. Mielina: fibre mieliniche e non mieliniche. Comunicazione sinaptica.

-Sangue: plasma e cellule (eritrociti, leucociti, piastrine)

 

Embriologia:

-Gametogenesi

-Fecondazione

-Prima settimana

-Seconda settimana 

-Terza settimana

-Quarta settimana: formazione dell’embrione

-Principi e meccanismi di morfogenesi

-Neurulazione

-Somiti e derivati

-Placenta, allantoide, amnios, corion e sacco vitellino


Prerequisiti

Conoscenze scientifiche a livello di scuola secondaria superiore

Modalità didattica

Vedere “Fundamentals of Human Morphology”

Materiale didattico

Histology: A Text and Atlas, with Correlated Cell and Molecular Biology, 6th Edition 6th Edition

by Michael H. Ross PhD, Wojciech Pawlina MD.

 

Junqueira's Basic Histology: Text and Atlas, Thirteenth Edition by Anthony Mescher.

 

The developing human: Clinically oriented Embryology by Keith L. Moore and TVN Persaud.

Periodo di erogazione dell'insegnamento

Vedere “Fundamentals of Human Morphology”

Modalità di verifica del profitto e valutazione

Vedere “Fundamentals of Human Morphology”

Orario di ricevimento

Vedere “Fundamentals of Human Morphology”

Export

Aims

Students will be able to describe the structure and ultrastructure of the eukaryotic cell and the morphology correlate with the function of each organelle; then they will be able to describe the structure and morpho-functional characteristics of human tissues (epithelial, connective, muscle and nervous tissues) as well as to describe the main events of gametogenesis and early embryogenesis.

Contents

See “Fundamentals of Human Morphology”

Detailed program

- Histology and its methods of study

- Cytology: general properties of eukariotic cells

- Plasma membrane:  structure, molecular composition, functions. 

- Cell connections: tight junctions, gap junctions and desmosomes.

- Cytosol: molecular composition and functions

- Cytoplasmic organelles: Mitochondria, Ribosomes, Endoplasmic reticulum (rough and smooth), Golgi complex, Lysosomes, Peroxisomes

- Cytoskeleton: Microtubules, Actin filaments and intermediate filaments

- Trafficking, sorting and secretion of proteins

- Nucleus and nucleolus

- Cell death: Apoptosis and necrosis

 

Tissues:

- Epithelial tissue: covering epithelia and glandular epithelia. Microvilli, cilia, flagellum, stereocilia. Basement membrane.

- Connective tissue: cells, ground substance, fibers. Types of connective tissue: loose, dense irregular, dense regular, elastic connective tissue.

- Adipose tissue: unilocular and multilocular adipose tissue.

- Cartilage: hyaline, elastic and fibrocartilage.

- Bone: bone cells, bone matrix. Type of bone: primary and secondary bone tissue; compact and spongy bone. Histogenesis: intramembranous and endochondral ossification. Remodelling and repair.

- Muscle tissue: smooth, skeletal and cardiac muscle. Stimulation. Contraction. Regeneration.

- Nervous tissue: neurons and glial cells. Myelin: myelinated and unmyelinated fibers. Synaptc communication.

- Blood: plasma and cells (erythrocytes, leukocytes, platelets)

 

Embryology:

-Gametogenesis

-Fertilization 

-First Week 

-Second Week: Becoming Bilaminar and Fully Implanting

-Third Week: Becoming Trilaminar and Establishing Body Axes

-Fourth Week: Forming the Embryo

-Principles and Mechanisms of Morphogenesis 

-Neurulation

-Somites and derivatives 

-Placenta, allantoid, amnios, chorion and yolk sac

Prerequisites

College-level scientific knowledge

Teaching form

See “Fundamentals of Human Morphology”

Textbook and teaching resource

Histology: A Text and Atlas, with Correlated Cell and Molecular Biology, 6th Edition 6th Edition

by Michael H. Ross PhD, Wojciech Pawlina MD.

 

Junqueira's Basic Histology: Text and Atlas, Thirteenth Edition by Anthony Mescher.

 

The developing human: Clinically oriented Embryology by Keith L. Moore and TVN Persaud.

Semester

See “Fundamentals of Human Morphology”

Assessment method

See “Fundamentals of Human Morphology”

Office hours

See “Fundamentals of Human Morphology”

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Key information

Field of research
BIO/17
ECTS
2
Term
Second semester
Activity type
Mandatory
Course Length (Hours)
20
Degree Course Type
6-year single cycle Master Degree

Staff

    Teacher

  • VC
    Valentina Alda Carozzi
  • GC
    Guido Angelo Cavaletti

Enrolment methods

Manual enrolments
Self enrolment (Student)

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