- Medicine and Surgery
- Single Cycle Master Degree (6 years)
- Medicine and Surgery [H4102D]
- Courses
- A.A. 2020-2021
- 3rd year
- Hematology
- Summary
Course Syllabus
Obiettivi
In particolare lo studente è in grado di interpretare i segni, i sintomi ed i dati di laboratorio che caratterizzano:
- le leucemie acute mieloidi e linfoidi
- la leucemia mieloide cronica
- le malattie mieloproliferative croniche: la Policitemia Vera, la Trombocitemia Essenziale e la Mielofibrosi Idiopatica
- il linfoma Non Hodgkin indolente
- il linfoma Non Hodking aggressivo
- il Morbo di Hodking
- il Mieloma Multiplo
- le Gammopatie monoclonali di incerto significato (MGUS) e la macroglobulinemia di Waldenstrom
- l'anemia aplastica e l'Emoglobinuria Parossistica Notturna (EPN)
- le anemie emolitiche
- la Porpora trombocitopenica idiopatica
- trapianto autologo di cellule staminali emopoietiche
- trapianto allogenico di cellule staminali emopoietiche
- nuove immunoterapie (incluse le CAR-T)
Lo studente è in grado di descrivere i principi della diagnostica morfologica e molecolare delle malattie ematologiche e le basi della Medicina Trasfusionale.
Contenuti sintetici
HEMATOLOGY I
1. Clinical approach to the ambulatory patient presenting with hemorrhagic symptoms
2. Clinical approach to the ambulatory patient presenting with thrombotic symptoms
3. Management of the outpatient anticoagulation clinics
4. Laboratory diagnosis of coagulation disorders
5. Aphaeretic therapies
6. Blood transfusion therapy
7. Phlebotomy
8. Plasma exchange treatments
HEMATOLOGY II
1. The clinical history of Acute Leukemia
2. The clinical history of chronic myelogenous leukemia
3. The clinical history of Polycythemia Vera, Essential Thrombocythemia, Myelofibrosis
4. The clinical history of indolent Non-Hodgkin Lymphoma
5. The clinical history of aggressive Non-Hodgkin Lymphoma
6. The clinical history of Hodgkin Lymphoma
7. The clinical history of Multiple Myeloma
8. The clinical history of Monoclonal gammopathy of Undetermined Significance (MGUS) and Waldenstrom macroglobulinemia
9. The clinical history of aplastic anemia and nocturnal paroxysmal hemoglobinuria
10. The clinical history of hemolytic anemias
11. Autologous Hematopoietic stem cell transplantation
12. Allogeneic hematopoietic stem cell transplantation
13. New Immunotherapies (including CAR-T cells)
14. Immune Thrombocytopenic Purpura (ITP)
15. The morphologic diagnosis of hematologic diseases: principle of flow cytometry
16. The molecular diagnosis of hematologic diseases
Programma esteso
HEMATOLOGY I
1. Clinical approach to the ambulatory patient presenting with hemorrhagic symptoms
2. Clinical approach to the ambulatory patient presenting with thrombotic symptoms
3. Management of the outpatient anticoagulation clinics
4. Laboratory diagnosis of coagulation disorders
5. Aphaeretic therapies
6. Blood transfusion therapy
7. Phlebotomy
8. Plasma exchange treatments
HEMATOLOGY II
1. The clinical history of Acute Leukemia
2. The clinical history of chronic myelogenous leukemia
3. The clinical history of Polycythemia Vera, Essential Thrombocythemia, Myelofibrosis
4. The clinical history of indolent Non-Hodgkin Lymphoma
5. The clinical history of aggressive Non-Hodgkin Lymphoma
6. The clinical history of Hodgkin Lymphoma
7. The clinical history of Multiple Myeloma
8. The clinical history of Monoclonal gammopathy of Undetermined Significance (MGUS) and Waldenstrom macroglobulinemia
9. The clinical history of aplastic anemia and nocturnal paroxysmal hemoglobinuria
10. The clinical history of hemolytic anemias
11. Autologous Hematopoietic stem cell transplantation
12. Allogeneic hematopoietic stem cell transplantation
13. New Immunotherapies (including CAR-T cells)
14. Immune Thrombocytopenic Purpura (ITP)
15. The morphologic diagnosis of hematologic diseases: principle of flow cytometry
16. The molecular diagnosis of hematologic diseasesPrerequisiti
Basic Clinical Skills course
Modalità didattica
Practical guided observation activities with briefings and debriefings by hospital tutors
Materiale didattico
DA DEFINIRSI
Periodo di erogazione dell'insegnamento
SECONDO SEMESTRE
Modalità di verifica del profitto e valutazione
practical skills observation and rating scale assessment
Orario di ricevimento
SU APPUNTAMENTO
Aims
At the end of the clerkship the student has the knowledge to recognize and interpret the main diseases of the blood and lymphatic system.
In particular, the student is able to interpret the signs, symptoms and laboratory data that characterize:
- acute myeloid and lymphoid leukemias
- chronic myeloid leukemia
- chronic myeloproliferative diseases: polycythemia Vera, essential thrombocythemia and idiopathic myelofibrosis
- indolent Non-Hodgkin lymphoma
- aggressive Non-Hodking lymphoma
- Hodking Lymphoma
- Multiple Myeloma
- Monoclonal Gammopathies of Undetermined Significance (MGUS) and Waldenstrom macroglobulinemia
- aplastic anemia and nocturnal paroxysmal hemoglobinuria (EPN)
- hemolytic anemias
- idiopathic thrombocytopenic purpura (ITP)
Furthermore, the student has the knowledge to describe the main therapeutic tretments of the diseases described above, with particular attention to the methods of use of:
- autologous hematopoietic stem cell transplantation
- allogeneic transplantation of hematopoietic stem cells
- new immunotherapies (including CAR-T)
The student is able to describe the principles of the morphological and molecular diagnostics of the hematological diseases and the basis of the Transfusion Medicine.
Contents
HEMATOLOGY I
1. Clinical approach to the ambulatory patient presenting with hemorrhagic symptoms
2. Clinical approach to the ambulatory patient presenting with thrombotic symptoms
3. Management of the outpatient anticoagulation clinics
4. Laboratory diagnosis of coagulation disorders
5. Aphaeretic therapies
6. Blood transfusion therapy
7. Phlebotomy
8. Plasma exchange treatments
HEMATOLOGY II
1. The clinical history of Acute Leukemia
2. The clinical history of chronic myelogenous leukemia
3. The clinical history of Polycythemia Vera, Essential Thrombocythemia, Myelofibrosis
4. The clinical history of indolent Non-Hodgkin Lymphoma
5. The clinical history of aggressive Non-Hodgkin Lymphoma
6. The clinical history of Hodgkin Lymphoma
7. The clinical history of Multiple Myeloma
8. The clinical history of Monoclonal gammopathy of Undetermined Significance (MGUS) and Waldenstrom macroglobulinemia
9. The clinical history of aplastic anemia and nocturnal paroxysmal hemoglobinuria
10. The clinical history of hemolytic anemias
11. Autologous Hematopoietic stem cell transplantation
12. Allogeneic hematopoietic stem cell transplantation
13. New Immunotherapies (including CAR-T cells)
14. Immune Thrombocytopenic Purpura (ITP)
15. The morphologic diagnosis of hematologic diseases: principle of flow cytometry
16. The molecular diagnosis of hematologic diseasesDetailed program
HEMATOLOGY I
1. Clinical approach to the ambulatory patient presenting with hemorrhagic symptoms
2. Clinical approach to the ambulatory patient presenting with thrombotic symptoms
3. Management of the outpatient anticoagulation clinics
4. Laboratory diagnosis of coagulation disorders
5. Aphaeretic therapies
6. Blood transfusion therapy
7. Phlebotomy
8. Plasma exchange treatments
HEMATOLOGY II
1. The clinical history of Acute Leukemia
2. The clinical history of chronic myelogenous leukemia
3. The clinical history of Polycythemia Vera, Essential Thrombocythemia, Myelofibrosis
4. The clinical history of indolent Non-Hodgkin Lymphoma
5. The clinical history of aggressive Non-Hodgkin Lymphoma
6. The clinical history of Hodgkin Lymphoma
7. The clinical history of Multiple Myeloma
8. The clinical history of Monoclonal gammopathy of Undetermined Significance (MGUS) and Waldenstrom macroglobulinemia
9. The clinical history of aplastic anemia and nocturnal paroxysmal hemoglobinuria
10. The clinical history of hemolytic anemias
11. Autologous Hematopoietic stem cell transplantation
12. Allogeneic hematopoietic stem cell transplantation
13. New Immunotherapies (including CAR-T cells)
14. Immune Thrombocytopenic Purpura (ITP)
15. The morphologic diagnosis of hematologic diseases: principle of flow cytometry
16. The molecular diagnosis of hematologic diseasesPrerequisites
Basic Clinical Skills course
Teaching form
Practical guided observation activities with briefings and debriefings by hospital tutors
Textbook and teaching resource
TO BE DEFINED
Semester
SECOND TERM
Assessment method
practical skills observation and rating scale assessment
Office hours
APPOINTMENT BY EMAIL