Syllabus del corso
Obiettivi
Fornire allo studente le conoscenze sulle tecnologie e le piattaforme utilizzate in metabolomica in campo biomedico
Contenuti sintetici
Concetti e definizioni utilizzati in metabolomica. Strumentazione, tecnologie e approcci analitici utilizzati nello studio dei processi metabolici e delle loro alterazioni per indagini biomediche.
Programma esteso
Introduzione alla metabolomica: concetti, approcci e definizioni
Tecnologie analitiche di metabolomica
Disegno sperimentale in metabolomica
Lipidomica e Flussomica
Prerequisiti
Conoscenze di base di chimica, biochimica e statistica
Modalità didattica
Lezioni frontali; Esercitazioni
Materiale didattico
Review e articoli pubblicati su riviste internazionali verranno indicati durante il corso. Downard K., Mass spectrometry . A foundation course. Royal Society of Chemistry, 2004 ISBN 0-8504-609-7 Gary Siuzdak, Mass Spectrometry for Biotechnology, Academic Press 1996 Per consultazione: J. H. Gross, Mass Spectrometry. A Textbook, Berlin – Heidelberg, Springer Verlag, 2004 E. De Hoffmann, V. Stroobant, Mass Spectrometry. Principles and Application, 2nd Edition Chichester, John Wiley & Sons, 2001. C. Dass, Principles and Practice of Biological Mass Spectrometry, New York, Wiley-Interscience, 2000. ISBN 0471330531 Chapman, John R. Mass Spectrometry of Proteins and Peptides, Humana press 2000, ISBN 0- 89603-609-X Walker, John M. The Proteomics Protocols Handbook Humana Press, 2005
Periodo di erogazione dell'insegnamento
Secondo semestre
Modalità di verifica del profitto e valutazione
Una domanda sui contenuti del modulo è inserita nella prova scritta-orale del corso di Proteomica e Metabolomica
Orario di ricevimento
Ogni giorno previo appuntamento
Sustainable Development Goals
Aims
The course will introduce metabolomics technologies and platforms applied to biomedical investigations
Contents
Main concepts and definitions used in metabolomics. Analytical approaches and methods in used metabolomics
studies for biomedical investigations.
Detailed program
Introduction to metabolomics: concepts, approaches and definitions
Analytical technologies in metabolomics
Experimental design in metabolomics
Lipidomics and Fluxomics
Prerequisites
Basic knowledge in the field of Chemistry, Biochemistry and Statistics
Teaching form
Lectures and practical lessons
Textbook and teaching resource
Reviews e and scientific articles published on international journals will be provided during the course. Downard K., Mass spectrometry . A foundation course. Royal Society of Chemistry, 2004 ISBN 0-8504-609-7 Gary Siuzdak, Mass Spectrometry for Biotechnology, Academic Press 1996 Per consultazione: J. H. Gross, Mass Spectrometry. A Textbook, Berlin – Heidelberg, Springer Verlag, 2004 E. De Hoffmann, V. Stroobant, Mass Spectrometry. Principles and Application, 2nd Edition Chichester, John Wiley & Sons, 2001. C. Dass, Principles and Practice of Biological Mass Spectrometry, New York, Wiley-Interscience, 2000. ISBN 0471330531 Chapman, John R. Mass Spectrometry of Proteins and Peptides, Humana press 2000, ISBN 0- 89603-609-X Walker, John M. The Proteomics Protocols Handbook Humana Press, 2005
Semester
Second semester
Assessment method
One written and oral question is present during the exam of the Proteomics and Metabolomics course
Office hours
Every day upon appointment
Sustainable Development Goals
Staff
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Giuseppe Paglia
