Course Syllabus

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Il corso fornirà conoscenze di base sugli effetti di diversi farmaci su cuore e circolazione e spiegherà i meccanismi d'azione delle principali classi di farmaci cardiovascolari. Il corso consentirà agli studenti di comprendere come adattare la prescrizione dei farmaci in base alla malattia e alle caratteristiche del paziente. Dopo aver completato questo corso, gli studenti apprenderanno conoscenze di base sul trattamento delle principali condizioni cardiovascolari e respiratorie (ipertensione, cardiopatia ischemica, insufficienza cardiaca, asma ecc.).

Principali classi di farmaci cardiovascolari e respiratori con i loro meccanismi d'azione, interazioni farmacologiche e precauzioni

· Panoramica generale della terapia farmacologica per le malattie cardiovascolari
· Terapie anti-ischemiche e antianginose
· Terapie anti-ipertensive (agenti beta-bloccanti, calcio-antagonisti, inibitori del sistema renina-angiotensina-aldosterone, diuretici)
· Agenti antitrombotici (anticoagulazione acuta e cronica, fibrinolitici) - breve panoramica, come già discusso nelle malattie onco-ematologiche
· Agenti antipiastrinici - breve panoramica, come già discusso nelle malattie onco-ematologiche
· Terapie modificatrici dei lipidi (statine, fibrati, ezetimibe) - breve panoramica, come già discusso nelle malattie onco-ematologiche
· Farmaci anti-aritmici
· Trattamento dell'insufficienza cardiaca acuta e cronica
· Prodotti naturali nella medicina cardiovascolare
· Rischio contributivo e gestione delle comorbilità nell'insufficienza cardiaca cronica
· Farmaci non cardiaci che influenzano il cuore
· Trattamento dell'asma e della broncopneumopatia cronica ostruttiva

Conoscenze fondamentali di biologia cellulare e farmacologia generale

10 lezioni frontali

  • Kaski JC, Kjeldsen KP. The ESC Handbook on Cardiovascular Pharmacotherapy (2 edn). Oxford University Press 2019

  • Brunton L, Hilal-Dandan R, Knollmann BC. Goodman and Gilman's the Pharmacological Basis of Therapeutics (13th Edition) McGraw Hill 2018

Goodman and Gilman's The pharmacological basis of therapeutics, 13th ed. (2018) McGraw-Hill Education.

Primo semestre

Come per il vertical track (esame a risposta multipla e prova orale)

Su appuntamento via email a: antonio.torsello@unimib.it, laura.musazzi@unimib.it

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This course will provide basic knowledge about the effects of different drugs on heart and circulation and will explain the mechanisms of action of the main classes of cardiovascular drugs. The course will allow students understand how to tailor drug prescription according to patient disease and characteristics. After completion of this course, the students will learn basic knowledge about the treatment of major cardiovascular and respiratory conditions (hypertension, ischemic heart disease, heart failure, asthma etc).

Main classes of cardiovascular and respiratory drugs with their mechanisms of action, drug interactions and precautions

· General overview of pharmacologic therapy for cardiovascular diseases

· Anti-ischemic and antianginal therapies

· Anti-hypertensive therapies (Beta-blocking agents, Calcium channel blockers, Inhibitors of Renin-Angiotensin-Aldosterone System, Diuretics)

· Antithrombotic agents (acute and chronic anticoagulation, fibrinolytics) - brief overview, as already discussed in the Onco-Hematological diseases

· Antiplatelet agents - brief overview, as already discussed in the Onco-Hematological diseases

· Lipid-modifying therapies (statins, fibrates, ezetimibe) - brief overview, as already discussed in the Onco-Hematological diseases

· Anti-arrhythmic drugs

· Treatment of acute and chronic heart failure

  • Natural products in cardiovascular medicine

· Contributory risk and management of comorbidities in chronic heart failure

· Non-cardiac drugs affecting the heart

· Treatment of asthma and chronic obstructive pulmonary disease

Fundamental knowledge on cell biology and general pharmacology

10 frontal lessons

  • Kaski JC, Kjeldsen KP. The ESC Handbook on Cardiovascular Pharmacotherapy (2 edn). Oxford University Press 2019

  • Brunton L, Hilal-Dandan R, Knollmann BC. Goodman and Gilman's the Pharmacological Basis of Therapeutics (13th Edition) McGraw Hill 2018

Goodman and Gilman's The pharmacological basis of therapeutics, 13th ed. (2018) McGraw-Hill Education.

  • First semester

As for the vertical track (multiple choice exam and oral examination)

By email appointment at: antonio.torsello@unimib.it, laura.musazzi@unimib.it

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Key information

Field of research
BIO/14
ECTS
2
Term
First semester
Activity type
Mandatory
Course Length (Hours)
20
Degree Course Type
6-year single cycle Master Degree
Language
English

Staff

    Teacher

  • LM
    Laura Musazzi
  • AT
    Antonio Biagio Torsello

Enrolment methods

Manual enrolments
Self enrolment (Student)