Course Syllabus
Obiettivi
1) Understanding the pathology of cancer
2) Understanding the carcinogenic process and the transformed cell
3) Understanding initiation promotion progression
4) Understanding the tumor microenvironment
5) Understanding inflammation and cancer
6) Understanding carcinogenesis and tumor progression in breast colon and lung cancer
Targets in breast colon and lung cancer
Contenuti sintetici
1) cellular biochemical and molecular bases of the carcinogenic process
2) carcinogens, classification, action, DNA mutations, oncogenes
3) Components of the tumor microenvironment : angiogenesis, stroma, matrix
4) Components of the tumor infiltrate: natural and adaptive immunity cells in the cancer field
5) Growth factors and receptors in major tumors and their microenvironment; molecular bases of targeted therapy and immunotherapy
Programma esteso
1) cellular biochemical and molecular bases of the carcinogenic process
2) carcinogens, classification, action, DNA mutations, oncogenes
3) Components of the tumor microenvironment : angiogenesis, stroma, matrix
4) Components of the tumor infiltrate: natural and adaptive immunity cells in the cancer field
5) Growth factors and receptors in major tumors and their microenvironment; molecular bases of targeted therapy and immunotherapyPrerequisiti
basic pathology course (II yrs) , preparatory courses to the Vertical Tracks according to the regulation
Modalità didattica
lezioni frontali ed esercitazioni in piccolo gruppo
Materiale didattico
da definirsi
Periodo di erogazione dell'insegnamento
secondo semestre
Modalità di verifica del profitto e valutazione
esame integrato
Orario di ricevimento
su appuntamento
Aims
1) Understanding the pathology of cancer
2) Understanding the carcinogenic process and the transformed cell
3) Understanding initiation promotion progression
4) Understanding the tumor microenvironment
5) Understanding inflammation and cancer
6) Understanding carcinogenesis and tumor progression in breast colon and lung cancer: Targets in breast colon and lung cancer
Contents
1) cellular biochemical and molecular bases of the carcinogenic process
2) carcinogens, classification, action, DNA mutations, oncogenes
3) Components of the tumor microenvironment : angiogenesis, stroma, matrix
4) Components of the tumor infiltrate: natural and adaptive immunity cells in the cancer field
5) Growth factors and receptors in major tumors and their microenvironment; molecular bases of targeted therapy and immunotherapyDetailed program
1) cellular biochemical and molecular bases of the carcinogenic process
2) carcinogens, classification, action, DNA mutations, oncogenes
3) Components of the tumor microenvironment : angiogenesis, stroma, matrix
4) Components of the tumor infiltrate: natural and adaptive immunity cells in the cancer field
5) Growth factors and receptors in major tumors and their microenvironment; molecular bases of targeted therapy and immunotherapyPrerequisites
basic pathology course (II yrs) , preparatory courses to the Vertical Tracks according to the regulation
Teaching form
frontal lessons and small group activities
Textbook and teaching resource
to be defined
Semester
second term
Assessment method
integrated exam
Office hours
on appointment