Course Syllabus
Obiettivi
HEMATOLOGY I – Falanga
1. Understanding the biology and normal physiology of blood coagulation
2. Hemorrhagic diseases
3. Thromboembolic diseases
4. Cancer and Thrombosis
5. Thrombotic thrombocytopenic anemia
6. Principles and clinical practice of Blood transfusions
HEMATOLOGY II - Rambaldi
1. Understanding the anatomy, the normal physiology and the hierarchical organization of the normal bone marrow and of the hematopoietic system
2. Undestanding the molecular basis and the clinical behavior of the following diseases:
- anemias
- Hodgkin and Non-Hodgkin Lymphomas
- Multiple Myeloma and other plasma cell dyscrasias
- Chronic myeloproliferative disorders
- Myelodysplastic syndromes and acute myeloid leukemias
- Acute and chronic lymphocytic leukaemias
Contenuti sintetici
HEMATOLOGY I (Falanga)
1. Clinical approach to the ambulatory patient presenting with hemorrhagic symptoms
2. Clinical approach to the ambulatory patient presenting with thrombotic symptoms
3. Management of the outpatient anticoagulation clinics
4. Laboratory diagnosis of coagulation disorders
5. Apheretic therapies
6. Blood transfusion therapy
7. Phlebotomy
8. Plasma exchange treatments
HEMATOLOGY II
1. Master genes regulating normal hematopoiesis, biology of hematopoietic growth factors. Morphology and immunology of hematopoietic progenitor cells. Morphology of mature peripheral blood cells
2. Classification of anemias
3. Molecular genetics, histopathology, WHO classification and clinical findings of Hodgkin and Non-Hodgkin Lymphomas
4. Molecular genetics and clinical findings of Multiple Myeloma and other plasma cell dyscrasias
5. Molecular genetics, histopathology, WHO classification and clinical findings of Chronic myeloproliferative disorders
6. Molecular genetics, histopathology, WHO classification and clinical findings of Myelodysplastic syndromes and acute myeloid leukemias
7. Molecular genetics, histopathology, WHO classification and clinical findings of Acute and chronic lymphocytic leukaemia
Programma esteso
HEMATOLOGY I - Falanga
1. Clinical approach to the ambulatory patient presenting with hemorrhagic symptoms
2. Clinical approach to the ambulatory patient presenting with thrombotic symptoms
3. Management of the outpatient anticoagulation clinics
4. Laboratory diagnosis of coagulation disorders
5. Apheretic therapies
6. Blood transfusion therapy
7. Phlebotomy
8. Plasma exchange treatments
HEMATOLOGY II - Rambaldi
1. Master genes regulating normal hematopoiesis, biology of hematopoietic growth factors. Morphology and immunology of hematopoietic progenitor cells. Morphology of mature peripheral blood cells
2. Classification of anemias
3. Molecular genetics, histopathology, WHO classification and clinical findings of Hodgkin and Non-Hodgkin Lymphomas
4. Molecular genetics and clinical findings of Multiple Myeloma and other plasma cell dyscrasias
5. Molecular genetics, histopathology, WHO classification and clinical findings of Chronic myeloproliferative disorders
6. Molecular genetics, histopathology, WHO classification and clinical findings of Myelodysplastic syndromes and acute myeloid leukemias
7. Molecular genetics, histopathology, WHO classification and clinical findings of Acute and chronic lymphocytic leukaemia
8. Basis of hematopoietic stem cell transplantation
9. Novel cellular based immunotherapies
Prerequisiti
Basic Clinical Skills course
Modalità didattica
lezioni e attività a piccoli gruppi
Materiale didattico
da definire
Periodo di erogazione dell'insegnamento
secondo semestre
Modalità di verifica del profitto e valutazione
integrated oral exam
Orario di ricevimento
su appuntamento
Aims
HEMATOLOGY I – Falanga
1. Understanding the biology and normal physiology of blood coagulation
2. Hemorrhagic diseases
3. Thromboembolic diseases
4. Cancer and Thrombosis
5. Thrombotic thrombocytopenic anemia
6. Principles and clinical practice of Blood transfusions
HEMATOLOGY II - Rambaldi
1. Understanding the anatomy, the normal physiology and the hierarchical organization of the normal bone marrow and of the hematopoietic system
2. Undestanding the molecular basis and the clinical behavior of the following diseases:
- anemias
- Hodgkin and Non-Hodgkin Lymphomas
- Multiple Myeloma and other plasma cell dyscrasias
- Chronic myeloproliferative disorders
- Myelodysplastic syndromes and acute myeloid leukemias
- Acute and chronic lymphocytic leukaemias
Contents
HEMATOLOGY I (Falanga)
1. Clinical approach to the ambulatory patient presenting with hemorrhagic symptoms
2. Clinical approach to the ambulatory patient presenting with thrombotic symptoms
3. Management of the outpatient anticoagulation clinics
4. Laboratory diagnosis of coagulation disorders
5. Apheretic therapies
6. Blood transfusion therapy
7. Phlebotomy
8. Plasma exchange treatments
HEMATOLOGY II
1. Master genes regulating normal hematopoiesis, biology of hematopoietic growth factors. Morphology and immunology of hematopoietic progenitor cells. Morphology of mature peripheral blood cells
2. Classification of anemias
3. Molecular genetics, histopathology, WHO classification and clinical findings of Hodgkin and Non-Hodgkin Lymphomas
4. Molecular genetics and clinical findings of Multiple Myeloma and other plasma cell dyscrasias
5. Molecular genetics, histopathology, WHO classification and clinical findings of Chronic myeloproliferative disorders
6. Molecular genetics, histopathology, WHO classification and clinical findings of Myelodysplastic syndromes and acute myeloid leukemias
7. Molecular genetics, histopathology, WHO classification and clinical findings of Acute and chronic lymphocytic leukaemia
Detailed program
HEMATOLOGY I - Falanga
1. Clinical approach to the ambulatory patient presenting with hemorrhagic symptoms
2. Clinical approach to the ambulatory patient presenting with thrombotic symptoms
3. Management of the outpatient anticoagulation clinics
4. Laboratory diagnosis of coagulation disorders
5. Apheretic therapies
6. Blood transfusion therapy
7. Phlebotomy
8. Plasma exchange treatments
HEMATOLOGY II - Rambaldi
1. Master genes regulating normal hematopoiesis, biology of hematopoietic growth factors. Morphology and immunology of hematopoietic progenitor cells. Morphology of mature peripheral blood cells
2. Classification of anemias
3. Molecular genetics, histopathology, WHO classification and clinical findings of Hodgkin and Non-Hodgkin Lymphomas
4. Molecular genetics and clinical findings of Multiple Myeloma and other plasma cell dyscrasias
5. Molecular genetics, histopathology, WHO classification and clinical findings of Chronic myeloproliferative disorders
6. Molecular genetics, histopathology, WHO classification and clinical findings of Myelodysplastic syndromes and acute myeloid leukemias
7. Molecular genetics, histopathology, WHO classification and clinical findings of Acute and chronic lymphocytic leukaemia
8. Basis of hematopoietic stem cell transplantation
9. Novel cellular based immunotherapies
Prerequisites
Basic Clinical Skills course
Teaching form
lessons and small group activities
Textbook and teaching resource
to be defined
Semester
second term
Assessment method
integrated oral exam
Office hours
appointment by email