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Percorso della pagina
  1. Medicine and Surgery
  2. Single Cycle Master Degree (6 years)
  3. Medicine and Surgery [H4104D - H4102D]
  4. Courses
  5. A.A. 2021-2022
  6. 3rd year
  1. Hematology
  2. Summary
Unità didattica Course full name
Hematology
Course ID number
2122-3-H4102D058-H4102D075M
Course summary SYLLABUS

Blocks

Back to Clerkship 5

Course Syllabus

  • Italiano ‎(it)‎
  • English ‎(en)‎
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Obiettivi

Al termine del tirocinio lo studente possiede le conoscenze per riconoscere ed interpretare le principali malattie del sangue e del sistema emolinfopoietico.
In particolare lo studente è in grado di interpretare i segni, i sintomi ed i dati di laboratorio che caratterizzano: 
  • le leucemie acute mieloidi e linfoidi
  • la leucemia mieloide cronica
  • le malattie mieloproliferative croniche: la Policitemia Vera, la Trombocitemia Essenziale e la Mielofibrosi Idiopatica
  • il linfoma Non Hodgkin indolente
  • il linfoma Non Hodking aggressivo
  • il Morbo di Hodking
  • il Mieloma Multiplo
  • le Gammopatie monoclonali di incerto significato (MGUS) e la macroglobulinemia di Waldenstrom
  • l'anemia aplastica e l'Emoglobinuria Parossistica Notturna (EPN)
  • le anemie emolitiche 
  • la  Porpora trombocitopenica idiopatica
Inoltre lo studente possiede le conoscenze per descrivere le principali linee di terapia delle patologie sopra descritte, con particolare attenzione alle modalità di impiego di:

  • trapianto autologo di cellule staminali emopoietiche
  • trapianto allogenico di cellule staminali emopoietiche
  • nuove immunoterapie (incluse le CAR-T)

Lo studente è in grado di descrivere i principi della diagnostica morfologica e molecolare delle malattie ematologiche e le basi della Medicina Trasfusionale.


Contenuti sintetici

HEMATOLOGY I 

1. Clinical approach to the ambulatory patient presenting with hemorrhagic symptoms 

2. Clinical approach to the ambulatory patient presenting with thrombotic symptoms 

3. Management of the outpatient anticoagulation clinics

4. Laboratory diagnosis of coagulation disorders

5. Aphaeretic therapies

6. Blood transfusion therapy

7. Phlebotomy

8. Plasma exchange treatments


HEMATOLOGY II

1. The clinical history of Acute Leukemia

2. The clinical history of chronic myelogenous leukemia

3. The clinical history of Polycythemia Vera, Essential Thrombocythemia, Myelofibrosis

4. The clinical history of indolent Non-Hodgkin Lymphoma

5. The clinical history of aggressive Non-Hodgkin Lymphoma

6. The clinical history of Hodgkin Lymphoma

7. The clinical history of Multiple Myeloma

8. The clinical history of Monoclonal gammopathy of Undetermined Significance (MGUS) and Waldenstrom macroglobulinemia

9. The clinical history of aplastic anemia and nocturnal paroxysmal hemoglobinuria

10. The clinical history of hemolytic anemias

11. Autologous Hematopoietic stem cell transplantation

12. Allogeneic hematopoietic stem cell transplantation

13. New Immunotherapies (including CAR-T cells)

14. Immune Thrombocytopenic Purpura (ITP)

15. The morphologic diagnosis of hematologic diseases: principle of flow cytometry

16. The molecular diagnosis of hematologic diseases

Programma esteso

HEMATOLOGY I 

1. Clinical approach to the ambulatory patient presenting with hemorrhagic symptoms 

2. Clinical approach to the ambulatory patient presenting with thrombotic symptoms 

3. Management of the outpatient anticoagulation clinics

4. Laboratory diagnosis of coagulation disorders

5. Aphaeretic therapies

6. Blood transfusion therapy

7. Phlebotomy

8. Plasma exchange treatments


HEMATOLOGY II

1. The clinical history of Acute Leukemia

2. The clinical history of chronic myelogenous leukemia

3. The clinical history of Polycythemia Vera, Essential Thrombocythemia, Myelofibrosis

4. The clinical history of indolent Non-Hodgkin Lymphoma

5. The clinical history of aggressive Non-Hodgkin Lymphoma

6. The clinical history of Hodgkin Lymphoma

7. The clinical history of Multiple Myeloma

8. The clinical history of Monoclonal gammopathy of Undetermined Significance (MGUS) and Waldenstrom macroglobulinemia

9. The clinical history of aplastic anemia and nocturnal paroxysmal hemoglobinuria

10. The clinical history of hemolytic anemias

11. Autologous Hematopoietic stem cell transplantation

12. Allogeneic hematopoietic stem cell transplantation

13. New Immunotherapies (including CAR-T cells)

14. Immune Thrombocytopenic Purpura (ITP)

15. The morphologic diagnosis of hematologic diseases: principle of flow cytometry

16. The molecular diagnosis of hematologic diseases

Prerequisiti

Basic Clinical Skills course

Modalità didattica

Practical guided observation activities with briefings and debriefings by hospital tutors

Materiale didattico

DA DEFINIRSI

Periodo di erogazione dell'insegnamento

SECONDO SEMESTRE 

Modalità di verifica del profitto e valutazione

practical skills observation and rating scale assessment

Orario di ricevimento

SU APPUNTAMENTO 

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Aims

At the end of the clerkship the student has the knowledge to recognize and interpret the main diseases of the blood and lymphatic system.
In particular, the student is able to interpret the signs, symptoms and laboratory data that characterize:

  • acute myeloid and lymphoid leukemias
  • chronic myeloid leukemia
  • chronic myeloproliferative diseases: polycythemia Vera, essential thrombocythemia and idiopathic myelofibrosis
  • indolent Non-Hodgkin lymphoma
  • aggressive Non-Hodking lymphoma
  • Hodking Lymphoma
  • Multiple Myeloma
  • Monoclonal Gammopathies of Undetermined Significance (MGUS) and Waldenstrom macroglobulinemia
  • aplastic anemia and nocturnal paroxysmal hemoglobinuria (EPN)
  • hemolytic anemias
  • idiopathic thrombocytopenic purpura (ITP)

Furthermore, the student has the knowledge to describe the main therapeutic tretments of the diseases described above, with particular attention to the methods of use of:

  • autologous hematopoietic stem cell transplantation
  • allogeneic transplantation of hematopoietic stem cells
  • new immunotherapies (including CAR-T)

The student is able to describe the principles of the morphological and molecular diagnostics of the hematological diseases and the basis of the Transfusion Medicine.

Contents

HEMATOLOGY I 

1. Clinical approach to the ambulatory patient presenting with hemorrhagic symptoms 

2. Clinical approach to the ambulatory patient presenting with thrombotic symptoms 

3. Management of the outpatient anticoagulation clinics

4. Laboratory diagnosis of coagulation disorders

5. Aphaeretic therapies

6. Blood transfusion therapy

7. Phlebotomy

8. Plasma exchange treatments


HEMATOLOGY II

1. The clinical history of Acute Leukemia

2. The clinical history of chronic myelogenous leukemia

3. The clinical history of Polycythemia Vera, Essential Thrombocythemia, Myelofibrosis

4. The clinical history of indolent Non-Hodgkin Lymphoma

5. The clinical history of aggressive Non-Hodgkin Lymphoma

6. The clinical history of Hodgkin Lymphoma

7. The clinical history of Multiple Myeloma

8. The clinical history of Monoclonal gammopathy of Undetermined Significance (MGUS) and Waldenstrom macroglobulinemia

9. The clinical history of aplastic anemia and nocturnal paroxysmal hemoglobinuria

10. The clinical history of hemolytic anemias

11. Autologous Hematopoietic stem cell transplantation

12. Allogeneic hematopoietic stem cell transplantation

13. New Immunotherapies (including CAR-T cells)

14. Immune Thrombocytopenic Purpura (ITP)

15. The morphologic diagnosis of hematologic diseases: principle of flow cytometry

16. The molecular diagnosis of hematologic diseases

Detailed program

HEMATOLOGY I 

1. Clinical approach to the ambulatory patient presenting with hemorrhagic symptoms 

2. Clinical approach to the ambulatory patient presenting with thrombotic symptoms 

3. Management of the outpatient anticoagulation clinics

4. Laboratory diagnosis of coagulation disorders

5. Aphaeretic therapies

6. Blood transfusion therapy

7. Phlebotomy

8. Plasma exchange treatments


HEMATOLOGY II

1. The clinical history of Acute Leukemia

2. The clinical history of chronic myelogenous leukemia

3. The clinical history of Polycythemia Vera, Essential Thrombocythemia, Myelofibrosis

4. The clinical history of indolent Non-Hodgkin Lymphoma

5. The clinical history of aggressive Non-Hodgkin Lymphoma

6. The clinical history of Hodgkin Lymphoma

7. The clinical history of Multiple Myeloma

8. The clinical history of Monoclonal gammopathy of Undetermined Significance (MGUS) and Waldenstrom macroglobulinemia

9. The clinical history of aplastic anemia and nocturnal paroxysmal hemoglobinuria

10. The clinical history of hemolytic anemias

11. Autologous Hematopoietic stem cell transplantation

12. Allogeneic hematopoietic stem cell transplantation

13. New Immunotherapies (including CAR-T cells)

14. Immune Thrombocytopenic Purpura (ITP)

15. The morphologic diagnosis of hematologic diseases: principle of flow cytometry

16. The molecular diagnosis of hematologic diseases

Prerequisites

Basic Clinical Skills course

Teaching form

Practical guided observation activities with briefings and debriefings by hospital tutors

Textbook and teaching resource

TO BE DEFINED 

Semester

SECOND TERM

Assessment method

practical skills observation and rating scale assessment

Office hours

APPOINTMENT BY EMAIL

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Key information

Field of research
MED/15
ECTS
2
Term
Second semester
Activity type
Mandatory
Course Length (Hours)
16
Degree Course Type
6-year single cycle Master Degree
Language
English

Staff

    Teacher

  • AF
    Anna Falanga
  • FL
    Federico Lussana

Enrolment methods

Manual enrolments
Self enrolment (Student)

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