Course Syllabus

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Alla fine del corso lo studente sarà in grado di:
• Descrivere l'eziologia, l'epidemiologia (inclusa la via di trasmissione), il quadro clinico e il decorso naturale delle principali malattie infettive e sindromi infettive;
• Integrare tali conoscenze con la scelta del percorso diagnostico appropriato per ciascuna malattia o sindrome (inclusa l'anamnesi, l'identificazione di sintomi e segni rilevanti, valutazione di laboratorio, test radiologici, diagnosi di complicanze e diagnosi differenziale);
• Descrivere le misure terapeutiche e preventive per le principali malattie infettive e sindromi infettive;
• Conoscere i fondamenti della chemioterapia antimicrobica delle più importanti malattie infettive.

Principi di epidemiologia, diagnosi, trattamento e prevenzione delle principali malattie infettive
Diagnosi differenziale e gestione clinica delle principali sindromi correlate ad infezioni ( Infezioni Sistemiche, Sepsi, Infezioni dell'apparato Cardiovascolare, Infezioni osee ed articolari, Infezioni della cute e dei tessuti molli, Infezioni da microorganismi sessualmente trasmesse, Infezioni dell'apparato respiratorio e dell'apparato digerente, Infezioni intra addominali)
Gestione della terapia antimicrobica

Ø Infezioni sistemiche

  • Sepsi e shock settico
  • Febbre tifoide e brucellosi
  • Malattia di Lyme
  • Malattia da rickettsie
  • Infezioni virali sistemiche (EBV, CMV)
  • COVID-19 e altre malattie infettive emergenti

**Ø Infezioni del Sistema Nervoso centrale

  • Meningiti
  • Encefaliti e mieliti
  • Ascessi cerebrali, ascessi epidurali

Ø Infezioni respiratorie

  • Infezioni delle alte vie respiratorie
  • Infezioni delle basse vie respiratorie (inclusi concetti di base sulle Polmonite acquisite in comunità, sulle Polmoniti nosocomiali e sulle Polmoniti associate a ventilatore)
  • Influenza
  • Tuberculosi

Ø Infezioni cardiovascolari

  • Endocarditi infettive
  • Infezioni correlate al catetere venoso centrale
  • Miocarditi e pericarditi infettive

Ø Infezioni gastrointestinali ed epatobiliari*

  • Gastroenteriti e diarree infettive
  • Diarree associate all'uso di antibiotici ed infezioni da Clostridium difficile
  • Infezioni intra-addominali ( incluse appendiciti, colecistiti e peritoniti)

*Nota: Epatiti virali e Helicobacter pylori saranno trattati nel corso di gastroenterologia.

Ø Malattie tropicali & Infezioni parassitarie

  • Malaria
  • Schistosomiasi
  • Arbovirosi (febbre Gialla, Dengue, Chikungunya, West Nile Virus)

Ø Infezione della cute e dei tessuti molli

  • Celluliti
  • Erisipela
  • Gangrena
  • Fascite necrotizzante

Ø Infezioni muscolo-scheletriche

  • Spondilodisciti
  • Osteomieliti
  • Artriti (incluse infezioni della articolari protesiche)

Ø Malattia da HIV

  • Epidemiologia
  • Patogenesi
  • Storia naturale e principali malattie opportunistiche
  • Principi di terapia antiretrovirale
  • Trasmisssione verticale
  • Profilassi pre- e post-esposizione

Ø Infezioni delle vie urinarie

  • Cistiti
  • Pielonefriti
  • Prostatiti

Ø Infezioni sessualmente trasmesse

  • Sifilide
  • Gonorrea
  • Uretriti non-gonococciche
  • Malattia infiammatoria pelvica (PID)
  • Trichomoniasi

**Ø Infezioni Fungine endemiche e non endemiche

  • Infezioni da Candida species
  • Infezioni da Aspergillus species
  • Altre infezioni da lieviti e muffe
  • Criptococcosi, Istoplasmosi, Coccidiomicosi, Blastomicosi
  • Infezioni da Pneumocystis species

Conoscenze relative ai corsi propedeutici indicati nel regolamento del Corso di Laurea

Lezioni frontali, discussione di casi clinici.

Frederick Southwic – Infectious Diseases. A clinical short course. Mc Graw Hill. Fourth edition
Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2) 20th Edition
Uptodate https://www-uptodate-com.unimib.idm.oclc.org/contents/search

Secondo semestre

Esame orale.

Previo appuntamento da concordare via mail:

  • Per prof. Bonfanti Paolo: segreteria.malattieinfettive@asst-monza.it

  • marco.rizzi@unimib.it; mrizzi@asst-pg23.it

  • giuseppe.lapadula@unimib.it

-massimo.puoti@unimib.it

SALUTE E BENESSERE | PARITÁ DI GENERE | ACQUA PULITA E SERVIZI IGIENICO-SANITARI | LAVORO DIGNITOSO E CRESCITA ECONOMICA
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By the end of the course, the student will be able to:

  • Describe the etiology, the epidemiology (including the route of transmission), the clinical picture, and the natural course of the principal infectious diseases and infective syndromes;
  • Integrate such knowledge with the choice of the appropriate diagnostic path for each disease or syndrome (including anamnesis, identification of relevant symptoms and signs, laboratory assessment, radiological tests, diagnosis of complication, and differential diagnosis);
  • Describe the therapeutic and preventive measures for the principal infectious diseases and infective syndromes;
  • Know the fundamentals of antimicrobial chemotherapy for the most important infectious diseases.

Principles of epidemiology, diagnosis, treatment and prevention of Infectious Diseases.
Differential diagnosis and management of clinical syndromes related to infections ( Systemic infections, Sepsis, Infections of Cardiovascular System, Bone and Joint infections, Skin and Soft tissue infections, Sexually Transmitted Infections,Respiratory tract and Digestive tract infections, Intra Abdominal Infections)
Management of antimicrobial therapy

Ø Systemic Infectious Diseases

  • Sepsis and septic shock
  • Typhoid fever and brucellosis
  • Lyme disease
  • Rickettsial diseases
  • Systemic Viral Infections (EBV, CMV)
  • COVID-19 and other emerging infectious diseases

Ø Central Nervous System Infections

  • Meningitis
  • Encephalitis and myelitis
  • Brain abscesses, epidural abscesses

Ø Respiratory Infections

  • Upper respiratory tract infections
  • Lower respiratory tract infections (including basic concepts on Community Acquired Pneumonia, Health Care Associated Pneumonia, Ventilator Associated Pneumonia)
  • Influenza
  • Tuberculosis (including Latent Tuberculosis and basic notions on extra-pulmonary tuberculosis)

Ø Cardiovascular Infections

  • Infective endocarditis (including Cardiovascular Implantable Electronic Devices Infections)
  • Catheter-related infections
  • Myocarditis and infectious pericarditis (basic notions)

Ø Gastrointestinal and Hepatobiliary Infections*

  • Infectious diarrhea & gastroenteritis
  • Antibiotic-associated diarrhea and Clostridium difficile infection
  • Intra-abdominal infections (including appendicitis, colecystitis, peritonitis)

*Note: viral hepatitis and Helicobacter pylori are discussed in the gastroenterology course.

**** Ø Tropical Diseases & Parasitic Infections****

  • Malaria
  • Schistosomiasis
  • Arbovirosis (Yellow Fever, Dengue, Chikungunya, West Nile Virus)

**** Ø Skin and Soft Tissues Infections****

  • Cellulitis
  • Erysipelas
  • Gangrene
  • Necrotizing fascitis

**** Ø Musculoskeletal Infections****

  • Spondylodiscitis
  • Osteomyelitis
  • Arthritis (including prosthetic joint infections)**

**** Ø HIV disease
**

  • Epidemiology
  • Pathogenesis
  • Natural history & main opportunisms
  • Principles of antiretroviral therapy
  • Vertical transmission
  • Pre and post-exposure prophylaxis

**** Ø Urinary Tract infections****

  • Cystitis
  • Pyelonephritis
  • Prostatitis

**** Ø Sexually Transmitted Diseases****

  • A general introduction to epidemiology and prevention
  • Syphilis
  • Gonorrhea
  • Nongonococcal urethritis
  • Pelvic inflammatory disease (PID)
  • Trichomoniasis

**Ø Endemic and non endemic mycoses

  • Candida species
  • Aspergillus species
  • Other Yeasts and moulds infections
  • Criptococcus, Histoplasmosa, Coccidiodes species , Blastomyces
  • Pneumocystis species

Topics which will be discussed withing the Oncohematological Track

  • Vaccinations in the immunocompromised host
  • Infections in the immunocompromised host (including febrile neutropenia and infections in asplenic patients)

Topics which will be discussed withing the Woman and Child Track

  • Infections in pregnancy
  • Vertically Transmitted Infections
    Topics which will be discussed withing the Digestive System Track
  • Viral Hepatitis

Knowledge of the introductory courses indicated in the degree course regulations

Frontal lessons with audio-visual aids and open discussion in the classroom, clinical case discussions.

Frederick Southwic – Infectious Diseases. A clinical short course. Mc Graw Hill. Fourth edition
Harrison's Principles of Internal Medicine, Twentieth Edition (Vol.1 & Vol.2) 20th Edition
Uptodate https://www-uptodate-com.unimib.idm.oclc.org/contents/search

Second semester

Final oral examination with open questions to assess general knowledge on infectious diseases.

To get an appointment, please contact the teachers by e-mail:

· prof. Bonfanti Paolo: segreteria.malattieinfettive@irccs-sangerardo.it

· prof. Puoti Massimo: massimo.puoti@unimib.it

· prof. Rizzi Marco: marco.rizzi@unimib.it; mrizzi@asst-pg23.it

· prof. Lapadula Giuseppe: giuseppe.lapadula@unimib.it

GOOD HEALTH AND WELL-BEING | GENDER EQUALITY | CLEAN WATER AND SANITATION | DECENT WORK AND ECONOMIC GROWTH
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Key information

Field of research
MED/17
ECTS
3
Term
Second semester
Activity type
Mandatory
Course Length (Hours)
30
Degree Course Type
6-year single cycle Master Degree
Language
English

Staff

    Teacher

  • Massimo Puoti
    Massimo Puoti
  • SV
    Serena Venturelli

Students' opinion

View previous A.Y. opinion

Bibliography

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Enrolment methods

Manual enrolments
Self enrolment (Student)

Sustainable Development Goals

GOOD HEALTH AND WELL-BEING - Ensure healthy lives and promote well-being for all at all ages
GENDER EQUALITY - Achieve gender equality and empower all women and girls
CLEAN WATER AND SANITATION - Ensure availability and sustainable management of water and sanitation for all
DECENT WORK AND ECONOMIC GROWTH - Promote sustained, inclusive and sustainable economic growth, full and productive employment and decent work for all